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1.
International Journal of Pharmaceutical and Clinical Research ; 15(3):46-58, 2023.
Article in English | EMBASE | ID: covidwho-2274744

ABSTRACT

Background: Tonsillitis is a common public health problem seen by otorhinolaryngology surgeons. It has socio-occupational and economic impact. Most of the tonsillitis is treated by antibiotic but some can lead to life threatening complication if not treated on time and not diagnosed the impending complication. Aim and Objectives: The objective of this work was to study the epidemiological and complications profile of acute and chronic tonsillitis and their distribution, followed by final outcome of the treatment adopted in the ANIIMS Portblair, ENT Department. Material(s) and Method(s): This is a retrospective study over a 12-month period from September 2020 to Aug 2021 including 225 patients who presented with tonsillitis and/or their complications were analysed. Their demography, clinical findings, types of tonsillitis, month wise distribution of types of disease and final outcome after medical treatment was analyzed. Result(s): Two hundred and twenty five (225) patients were studied. The mean +/- SD of cases studied was 23.32 +/- 12.98 years with minimum - maximum age range was 02 - 60 years. In this study there were 92/225 (40.9%) males and 133/225 (59.1%) females with a male to female ratio of 1:1.44. 76.88% of the patients showed a good outcome, 14.22% showed a moderate outcome, 07.55% showed an average outcome and 00.88% showed poor outcome. 19/ 225 (08.44%) of the patients who showed poor and average response were advised tonsillectomy after the COVID-19 pandemic in this study. Conclusion(s): Chronic Tonsillitis was a common throat disorder observed during COVID-19 pandemic. Males were more commonly affected. The increased attendance of patient's throat complaints was high due to awareness and similarity of symptoms of tonsillitis and COVID-19 disease. Low socio economic groups were more affected. The common types of tonsillitis were parenchymatous type, follicular type. Complications due to acute infection frequently observed were peritonsillar abscess, neck abscess. Medical treatment with Amoxycillin and clavulinic acid combination was highly responsive with 76.88% responding well.Copyright © 2023, Dr Yashwant Research Labs Pvt Ltd. All rights reserved.

2.
Reproductive Endocrinology ; - (61):8-14, 2021.
Article in Ukrainian | EMBASE | ID: covidwho-1614416

ABSTRACT

Research objective: to determine the risk factors for the spread of coronavirus infection among women of fertile age. Materials and methods. Authors analyzed the medical records (case histories and questionnaires) of 60 women of fertile age who were treated for coronavirus disease. After analysis of medical and social factors women were divided into age groups. Analysis of risk factors for coronavirus disease was determined by calculating the odds ratio according to Wald at p < 0.05. Results. Evaluation of the odds ratio of the COVID-19 chances depending on the nature of work of women of different ages showed that with intense work the risk of disease increases 2.5 times in the age group up to 30 years, which also confirms the analysis of previous indicators, that younger women with moderate workloads have more opportunities to attend mass events and crowds. In the structure of extragenital diseases in women with coronavirus disease, the chances of disease increased 2.6 times in those women who had a history of chronic tonsillitis. Among the history of infectious diseases, the chance ratio of coronavirus disease was increased in women over 30 years of age who had pertussis. Such data may indicate a similar mechanism of development of these diseases, because the causative agent of pertussis also penetrates the upper respiratory tract and may be accompanied by neurological symptoms – the appearance of seizures and bronchospasm. Conclusions. The data obtained in this way allow us to separate a narrower cohort of women of fertile age who may develop coronavirus disease. This will further allow developing proposals for a more efficient distribution of vaccines among the female population of Ukraine and reduce the prevalence of coronavirus infection.

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